Although pain is a multidimensional and subjective experience, its quantification via objective parameters is essential for neurophysiological research. Quantitative Sensory Testing (QST), conducted in our laboratory, is an advanced method that quantitatively evaluates the functionality of the somatosensory system through standardized psychophysical stimuli.
Unlike conventional electrophysiology, QST comprehensively analyzes large myelinated (Aβ), small myelinated (Aδ), and unmyelinated (C) nerve fibers. Our non-invasive test protocol encompasses the measurement of sensory perception and pain thresholds in response to thermal and mechanical stimuli, along with the objective assessment of phenomena such as allodynia and hyperalgesia.
Conducted under controlled, distraction-free conditions, these measurements serve as a fundamental research tool in elucidating the pathophysiology of chronic pain conditions, particularly polyneuropathies, migraines, and demyelinating diseases. Consequently, the integrity of the somatosensory pathways is mapped with high reliability.