Advanced Microscopic Neuroimaging

Widefield, DIC

Widefield (WF) mode (sample illumination with arc lamp), Laser WF mode (sample illumination with laser)

Lattice SIM

Structured Illumination Microscopy, allowing fast and gentle super-resolution imaging (~120 nm in xy and ~300 nm in z) in 3 dimensions.

Lattice SIM² 

The new SIM² module doubles the conventional SIM resolution and achieves up to ~60 nm laterally and ~200 nm axially. The Lattice SIM illumination allows for a better signal to noise ratio, more gentle imaging and can reach up to 255 fps during time lapse acquisition, well suited to capture highly dynamic biological processes in live samples. It further allows deeper imaging of samples up to around 70 µm thickness in comparison to only 20 µm of sample thickness in classical SIM. The speed of this imaging modality is well suited to capturing dynamic biological processes in live samples (significantly faster than regular laser scanning confocal).

Apotome

Grid-based optical sectioning to create highly contrasted images with high lateral and axial resolution. The Apotome mode is also amenable to SIM2 processing, allowing for high speed acquisition with high contrast, high resolution and low phototoxicity. In combination with SIM2 module, apotome imaging can get lateral rsoltuion down to ~110 nm and axial resolution to ~300 nm. ApoTome imaging is also faster than classic SIM and laser scanning microscopes, allowing for time lapse imaging of faster cellular/tissue dynamics.

SMLM

Single-molecule localization microscopy like dSTORM, PALM and PAINT allowing resolution down to ~20-30 nm in xy and ~50-80 nm in z.  

Dual filter sets for Duolink optimized for

dual color and double dual color applications

Filter sets are optimized for dual camera applications, maximum sensitivity, minimal cross-talk and reduced autofluorescence

Incubation

Co2 ,Humudity,Temprature

Bio Apps

• The Cell Counting app performs proliferation or survival assays.
• The Confluency app is used for scratch assays.
• The Gene Expression app measures cellular transfections or apoptosis.
• The Spot Detection app simplifies the identification of nuclear speckles or cellular vesicles

Arivis 4D

• Immediate visualization, annotation and analysis on workstations and notebooks in 2D, 3D and 4D, regardless of image size
• Easy to set up and train integrated AI, Machine Learning or Deep Learning models for segmentation, image processing and object classification for quick, reliable and reproducible results

• Distance measurements, compartmentalization and classification
• Powerful analysis pipeline for 3D/4D image analysis (cell segmentation, tracking, tracing, annotation, quantitative measurement and statistics)
• High resolution images and movies for rapid publication and awesome presentation of your research data

Available Optics