Projects

Ongoing Projects

Neuroscience and Neurotechnology Center of Excellence (NÖROM) Infrastructure Project

Supporting Organization: Presidency of the Republic of Turkey, Strategy and Budget Directorate, Infrastructure Project

Project Partners: Gazi University (Coordinating Institution), Ankara University, Middle East Technical University

Conducted under the coordination of Gazi University Scientific Research Projects Unit.

Executive: Prof. Dr. Hayrunnisa Bolay Belen (Gazi University), Prof. Dr. Meltem Bahçelioğlu (Gazi University), Prof. Dr. Nihal Apaydın (Ankara University), Prof. Dr. Güvem Gümüş Akay (Ankara University), Prof. Dr. Yeşim Aydın Son (METU), Assoc. Prof. Ali Emre Turgut (METU)

Detailed Information

Identification of a diagnostic neuroinflammatory biomarker panel for chronic migraine headache

Supporting Organization: TÜBİTAK 1004

ExecutiveProf. Dr. Hayrunnisa Bolay Belen (Gazi University)

Identification of Neuroimaging Marker Candidates for Diagnosis and Monitoring of Migraine-Related Sensory Processing Disorder and Development of an Objective Pain Measure from Facial Image Patterns

Supporting Organization: TÜBİTAK 1004

ExecutiveProf. Dr. Hayrunnisa Bolay Belen (Gazi University)


Development of GBA1-Mutant Midbrain Organoid Disease Models and Detailed Investigation of Histological, Biochemical, Multi-Omic and Metabolic Differences

Supporting Organization: TÜBİTAK/COST

Executive: Assoc. Prof. Burak Derkuş (Ankara University)

Project Team: Dr. Bekir Salih, Dr. Emirhan Nemutlu, Dr. Rezzak Yılmaz, Dr. Gökhan Çağlayan, Dr. Cemil Can Eylem

 

Detailed Investigation of the Effects of Pathogenic Microbial Extracellular Vesicle-Mediated exRNA Transport on Neurodegeneration in Brain Organoid Models

Supporting Organization:TÜBİTAK/COST

Executive: Assoc. Prof. Burak Derkuş (Ankara University)

Project Team: Dr. Bekir Salih, Dr. Cemil Can Eylem, Dr. Pınar Aytar Çelik


Hydrotherabots: Hydrotherapy Using Robots, AI, and VR Technologies for Physical Rehabilitation

Supporting Organization: TÜBİTAK-Qatar Research, Development and Innovation Authority (QRDI) Bilateral Cooperation Project

Executive: Si̇movate Bi̇li̇şi̇m Anoni̇m Şi̇rketi̇
Ankara University(Asst. Prof. Kutluk Bilge Arıkan)
Ted University(Prof. Dr. Gökçe Nur Yilmaz)
Gazi University(Prof. Dr. Murat Zi̇nnuroğlu)
Qatar University
Hamad Health Group

Multifaceted Evaluation of the Effect of Nicotinamide Mononucleotide Supplementation on the Neurotransmitter Profile in Rats with an Established Depression Model

Project Type: Thesis Project, Postgraduate

Project Team: Prof. Dr. Meltem Bahçelioğlu, Özlem Cemile Demirkesen (Student)


A Study on Predicting the Response of the Patient Population to RTMS Treatment Using Neuroplasticity Markers in Alzheimer's Disease and the Diagnostic Value of Cortical Extability Parameters

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Prof. Dr. Bülent Cengiz (Gazi University)

Social Cognition in Drug-Resistant Epilepsy Patients Treated with Vagus Nerve Stimulation, Resective Surgery, and Pharmacological Therapy: A Prospective Comparison

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Assoc. Prof. Simge Aykan (Ankara University)

Project Team: Prof. Dr. İrem Yıldırım (Gazi University), Assoc. Prof. Aslı Akyol Gürses (Gazi University), Assoc. Prof. Burak Karaaslan (Gazi University), Assoc. Prof. İrem Ekmekçi Ertek (Gazi University), Asst. Prof. Kutluk Bilge Arıkan (Ankara University)

Multisensory Processing and the Temporal Dynamics of Perception in Schizophrenia

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Prof. Dr. Hacı Hulusi KAFALIGÖNÜL (Gazi University)

Researcher: Asst. Prof. Hayriye AKTAŞ DİNÇER

Advisor: Prof. Dr. Salih BATTAL

A Neurolinguistic Approach to Diagnosing Dyslexia in School-Age Children: Examination and Comparison of Phoneme Discrimination, Word and Text Reading Processes Using Psychometric, Electrophysiological, and Eye-Tracking Techniques

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Asst. Prof. Sema Acar Ünalgan (İzmir Bakırçay University)

Project Team: Prof. Dr. Özgür Aydın, Asst. Prof. Esmehan Özer, Lect. Dr. Hazal Artuvan Korkmaz, Lect. Dr. R. Duygu Temeltürk


Comparison of Multiple Sensory Integration Processes Using a Virtual Dynamic Interaction System and Electroencephalography in Migraine Patients and Healthy Individuals

Supporting Organization: TÜBİTAK

ExecutiveProf. Dr. Hayrunnisa Bolay Belen (Gazi University)

Semantic Distance in Semantic Categorization, Neural Activity, GABA/Glutamate Balance, and PUP

Supporting Organization: TÜBİTAK

Executive:Asst. Prof. Emre Mısır (Başkent University)

Investigation of the Effects of Agonists and Positive Allosteric Modulators of Nicotinic Alpha-7 Receptors and AMPA Receptors on Cognitive Functions in Insomnia Animal Models

Supporting Organization: TÜBİTAK (ARDEB 1002)

Executive: Prof. Dr. Canan Uluoğlu (Gazi University)

Project Team: Res. Asst. Dr. Gökçen Paykal, Lect. Dr. Muhammed Cihan Güvel, Uzm. Dr. Utku Aykan

Detailed Information

Acoustic Phonological Perspectives on the Production Processes of Compound Words in Spoken Turkish

Supporting Organization: TÜBİTAK 1002-A Short Term Support Module

Executive: Assoc. Prof. İpek Pınar Uzun (Ankara University)


Investigation of Plasma-Derived Exosomal miR135a-5p Expression in Autism Spectrum Disorder

Supporting Organization: TÜSEB

Executive: Prof. Dr. Güvem Gümüş Akay (Ankara University)

Project Team: Assoc. Prof. Merve Çıkılı Uytun, Assoc. Prof. Nuray Varol

Investigating the effects of virtual reality-based surgical training on brain dynamics

Supporting Organization: TÜSEB

Executive: Asst. Prof. Hasan Onur KELEŞ (Ankara University)

Investigation of the Relationship Between Exposome Score and Telomere Length for Schizophrenia in Patients, Unaffected Siblings, and Control Groups

Supporting Organization: TÜSEB

ExecutiveProf. Dr. Güvem Gümüş Akay (Ankara University)

Project Team: Prof. Dr. Meram Can Saka, Assoc. Prof. Gamze Erzin, Lect. Dr. Öykü Mançe Çalışır

Investigation of the Effect of the SPOCK1 Protein Associated with Alzheimer's Disease on Apoptosis in Neurons

Supporting Organization: TÜSEB

Executive: Prof. Dr. Yeşim Aydın Son (METU)

Project Team: Emilia Ekenel (METU), Nazlı Çakır (METU), Res. Asst. Hüseyin Cahit Burduroğlu (METU)

The effect of math anxiety and educational practice on brain activity during numerical tasks

Supporting Organization: TÜSEB

Executive:Prof. Dr. Metehan Çiçek (Ankara Medipol University)

Project Team: Prof. Dr. Nihal APAYDIN, Assoc. Prof. Kevser AKTAŞ, Simge ALTINOK

Longitudinal evaluation of surgical assistants' skill and performance development using a multi-faceted approach

Supporting Organization: TÜSEB

Executive: Asst. Prof. Hasan Onur KELEŞ (Ankara University)

A Drug Repositioning Study for Preventing Addiction Through Genomic Modeling of Tobacco Use Disorder and Neurological Mechanisms

Supporting Organization: TÜSEB

Executive: Prof. Dr. Yeşim Aydın Son (METU)

Project Team: Gizem Arslantaş (METU), Nazlı Çakır (METU), Res. Asst. Hüseyin Cahit Burduroğlu (METU)


Investigating the Effects of Migraine Triggers on Mitochondria in iPSC-Derived Neuronal Organoids

Executive: Prof. Dr. Hayrunnisa Bolay Belen (Gazi University)

Project Code: TUİ-2026-10475

Project Type: International Research Cooperation Projects

Estimated End Date: 2028-02-07


The Relationship Between Intestinal Permeability and Inflammation in Patients with Ulcerative Colitis and Cognitive Function and Pain

Supporting Organization: Gazi University BAP

Executive: Asst. Prof. Ali Karataş (Gazi University)

Project Code: TSG-2025-10666

Project Type: Guided Project

Project Team: Prof. Dr. Mehmet Cindoruk, Prof. Dr. Hayrunnisa Bolay Belen, Prof. Dr. Meltem Bahçelioğlu, Prof. Dr. Tarkan Karakan, Dr. Hale Gök Dağıdır, Dr. İlkem Güzel, Prof. Dr. Ayşe Dursun, Asst. Prof. Zeynep Yığman, Asst. Prof. Kerem Atalar


Detailed Investigation of the Effects of Extracellular Vesicles on Brain Organoids

Supporting Organization: ADEP

Executive:  Assoc. Prof. Burak Derkuş

Project Team: Dr. Pınar Aytar Çelik, Dr. Ülkü Güler

Serum Neuronal Exosome Alpha-Synuclein Profile in the Diagnosis of Parkinson's Disease

Supporting Organization:ADEP

Executive: Dr. Mehmet Gökhan Çağlayan

Project Team: Assoc. Prof. Burak Derkuş (Ankara University)

 

 

Investigation of Candidate Biomarkers Using Comparative Transcriptome Analysis in Anesthesia-Related Postoperative Cognitive Impairment

Supporting Organization: AÜBAP-ADEP

Executive: Prof. Dr. Güvem Gümüş Akay (Ankara University)

Project Team: Prof. Dr. Başak Ceyda Meço, Prof. Dr. Meram Can Saka, Assoc. Prof. Beyza Doğanay Erdoğan

Clinical Evaluation of Genomic Diversity in Sarcomeric Protein Families Using Evolutionary and Functional Analysis-Based Machine Learning Models

Supporting Organization: ADEP

Executive: Prof. Dr. Yeşim Aydın Son (METU)

Project Team: Dr. Emrah Akkoyun (METU), Dr. Elif Güney (METU)


Investigation of the Efficacy of Soluble Epoxide Hydrolase (sEH) Inhibitors in a Paclitaxel-Induced Neuropathic Pain Model

Supporting Organization: Gazi University BAP

Executive: Assoc. Prof. Nur Banu Bal (Gazi University)

Project Code: TOA-2025-10190

Project Type: Priority Area Research Project

Project Team: Prof. Dr. Erden Banoğlu, Prof. Dr. Burcu Çalışkan, Prof. Dr. Hayrunnisa Bolay Belen, Prof. Dr. Meltem Bahçelioğlu, Asst. Prof. Deniz Lengerli, Asst. Prof. Kübra Çalışkan, Asst. Prof. Kerem Atalar, Dr. Hale Gök Dağıdır, Assoc. Prof. Zehra Tuğçe Gür Maz

Effects of Melatonin, Ramelteon, and Agomelatine on Mood Changes, Cognitive Functions, and IGF-1 Levels in Mice with Chronic Sleep Deprivation

Supporting Organization: Gazi University BAP

Executive: Prof. Dr. Canan Uluoğlu (Gazi University)

Project Team: Res. Asst. Dr. Gökçen Paykal, Lect. Dr. Muhammed Cihan Güvel, Uzm. Dr. Utku Aykan

The Investigation of the Effects of Pesticides on Dopaminergic Neuron Damage in Midbrain Organoid Models

Supporting Organization: BAP

Executive: Assoc. Prof. Burak Derkuş (Ankara University)

Project Team: Dr. Rezzak Yılmaz, Dr. Gökhan Çağlayan, Dr. Demet Cansaran Duman, Melis Işık

 

Examination of the Effects of Bisphenol F Administration During the Perinatal Period on the Development of Gastrointestinal Neuronal Structures

Supporting Organization: Gazi University BAP

Executive: Prof. Dr. Meltem Bahçelioğlu (Gazi University)

Project Code: TDK-2025-10349

Project Type: Thesis Project, Postgraduate

Project Team: Hatice Büşra Erdoğan Aybey (Thesis Student), Asst. Prof. Kerem Atalar (Gazi University)

Investigating the Effects of Transauricular Vagal Nerve Stimulation on Neurodevelopment in Different Regions of the Brain in an Experimental Autism Model

Project Type: Priority Area Research Project

Project Team: Asst. Prof. Kerem Atalar, Asst. Prof. Zeynep Yığman, Lect. PhD Elif Gülçiçek Abbasoğlu Topa, Ayşen Çalıkuşu (Graduate Student), Ramazan Öngen (Student), Muhammed Berkay Doğru (Student)

Development of New Protocols for the Creation of Midbrain Organoids

Supporting Organization: Ankara University BAP

Executive:Prof. Dr. Güvem Gümüş Akay (Ankara University)

Investigation of the Effect of Sulodexide on Reperfusion Injury via the NLRP3-Mediated Pyroptosis Pathway in Rats Undergoing Testicular Torsion Detorsion

Supporting Organization: Gazi University BAP

Executive: Asst. Prof. Zeynep Yığman (Gazi University)

Transparentization of mouse brains at different ages using the iDISCO+ protocol and three-dimensional imaging of neural structures using a BIII tubulin antibody with lightsheet microscopy

Supporting Organization: Gazi University BAP

Executive: Asst. Prof. Kerem Atalar (Gazi University)

Effects of Chronic 2,4-Dinitrophenol Administration in a Depression Animal Model on Mood and Cognitive Functions

Supporting Organization: Gazi University BAP

Executive:Prof. Dr. Canan Uluoğlu (Gazi University)

Project Team: Res. Asst. Dr. Gökçen Paykal, Lect. Dr. Muhammed Cihan Güvel, Uzm. Dr. Utku Aykan


Completed Projects

Development of a Robotic Mirror Therapy System for the Hand Based on Motor Learning

Supporting Organization: TÜBİTAK

ExecutiveAsst. Prof. Kutluk Bilge Arıkan (Ankara University)

Detailed Information

The Effect of Transauricular Vagal Stimulation on Pain Pathways in an Experimental Colitis Model

Supporting Organization: Gazi University BAP

Executive:  Prof. Dr. Neslihan Bukan (Gazi University)

Investigation of the effects of transauricular vagus nerve stimulation on nervous system development and morphology, biochemical markers, and behavior in an experimental autistic mouse model

Supporting Organization: Gazi University BAP

Executive: Prof. Dr. Meltem Bahçelioğlu (Gazi University)

Investigation of the Effects of Transauricular Vagal Stimulation on Synapse Formation in the Enteric Nervous System and Intestinal Morphometry in an Experimental Colitis Model

Supporting Organization: Gazi University BAP

Executive: Prof. Dr. Meltem Bahçelioğlu (Gazi University)

Investigation of the Effects of Transauricular Vagal Nerve Stimulation on the Limbic System in an Inflammatory Bowel Disease Model

Supporting Organization: Gazi University BAP

Executive:  Prof. Dr. Meltem Bahçelioğlu (Gazi University)

The Effect of Visual Cue-Induced Craving on Brain Oscillations in Patients with Alcohol Use Disorder: An Electroencephalography Study

Supporting Organization: Ankara University BAP

Executive:  Prof. Dr. İnci İlhan (Ankara University), Prof. Dr. Canan Kalaycıoğlu (Ankara University)

The Effect of Social Stress on Time Perception: An Epigenetic and Brain Imaging Study

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Prof. Dr. Metehan Çiçek (Ankara Medipol University)

Project Team: Prof. Dr. Güvem Gümüş Akay, Asst. Prof. Sertaç Üstün, Assoc. Prof. Nuray Varol

Detailed Information

Investigation of the Effects of Transauricular Vagus Stimulation on Pro- and Anti-Inflammatory Cytokines in an LPS-Induced Cytokine Storm Model

Supporting Organization: Gazi University BAP

ExecutiveProf. Dr. Meltem Bahçelioğlu (Gazi University)

Evaluating the Common Mechanisms of Space, Time, and Number Perception from the Perspectives of Magnitude Theory and Metric Error Tracking: A Neuroimaging and Neuromodulation Study

Supporting Organization: TÜBİTAK (ARDEB 1001)

Executive: Prof. Dr. Metehan Çiçek (Ankara Medipol University)